I-95
Runs from the Florida state line near St. Mary's to the South Carolina line north of Savannah, south to north.
| I-95 |
| Exit Number | |
| St. Mary’s Road (CR 61) |
| 1 | |
| SR 40/Kingsland/St. Mary’s Rd. |
| 3 | |
| Laurel Island Pkwy. (CR 90) |
| 6 | |
| Harrietts Bluff Rd. (CR 141) |
| 7 | |
| SR 25 Spur |
| 14 | |
| Dover Bluff Rd. (CR 145) |
| 26 | |
| US 17/US 82/SR 520/S. Georgia Pkwy. |
| 29 | |
| SR 27/US 341 |
| 36A/B | |
| SR 25 Spur/N. Golden Isle/Veterans Memorial Pkwy. |
| 38 | |
| SR 99/Grant Ferry Road |
| 42 | |
| SR 251/Briardam Road |
| 49 | |
| SR 57/Wiregrass Trail |
| 58 | |
| SR 25/US 17/Ocean Hwy. |
| 67 | |
| SR 38/US 84/Sunbury Rd. |
| 76 | |
| SR 25/US 17/Ocean Hwy. |
| 87 | |
| SR 144/Old Clyde Road |
| 90 | |
| SR 204/Bacon Highway |
| 94 | |
| I-16/James Gillis Mem. Hwy. |
| 99A/B | |
| SR 26/US 80/Louisville Hwy. |
| 102 | |
| Airways Avenue |
| 104 | |
| Jimmy Deloach Pkwy. (proposed) n/a |
| 106 | |
| SR 21/Augusta Road |
| 109 | |